Alright, so from this side, from this left side, or at least what we are It's a new tool I'm using, so let me make sure I'm doing it right. So let me get my pen tool out now, let me deselect this, And then you would have two strands, two identical strands of the DNA. Them two sides of the ladder, that either side could be used You were to split these, these things you could call And then I copy and then I paste, and it's just like that. And then there we go, a little bit of it isĭropping below the video but I think that serves the purpose. So let me copy and paste, so if I take that side right over there, so let me copy and then paste it. Two sides of the ladder, and actually let's do that. And replication, you can imagine taking either splitting these The different processes next to each other. Introduction video as well, but it's nice to see So how does DNA replicate? And this process is called replication. As a cell divides, the two new cells would want to have the same genetic material. Or we would need to beĪble to replicate it. Molecular basis of heredity would need to do. So once again it mightīe part of a molecule that has not seven or eight base pairs, but might have 70 million base pairs. Very, very small section, let me do this in a different color, this little section right over here, zoomed in. So for example this might be a section of a much longer molecule, so the much longer strand of DNA, and even there I'm probably And just to be clear,Īnd we talked about this in the introductory video to DNA, DNA is much more than, you So right over here thisĬould be a fragment of DNA, I have, what, I have- This is eight base pairs depicted. ![]() Really just give you theĬonceptual idea of what happens. ![]() On a conceptual level, I'm not gonna go into all of the, I guess you could say biochemical details. And what we wanna do in this video is get a better appreciationįor why it is suitable, and the mechanism by which it is the molecular basis for heredity. Talked about how DNA's structure as this double helix, this twisted ladder, makes it suitable for being the Eventually, the RNA transcript is released, and the polymerase detaches from the DNA. In the wake of transcription, the DNA strands re-form a double helix. The polymerase moves downstream, unwinding the DNA and elongating the RNA transcripts 5' -> 3'. After RNA polymerase binds to the promoter, the DNA strands unwind, and the polymerase initiates RNA synthesis at the start point on the template strand. The DNA double helix then unwinds, and RNA synthesis begins at the start point on the template strand of DNA.ġ) Initiation. 3) Additional transcription factors bind to the DNA along w/ RNA polymerase II, forming the transcription initiation complex. 2) Several transcription factors, one recognizing the TATA box, must bind to the DNA before RNA polymerase II can do so. 1) A eukaryotic promoter commonly includes a TATA box, a nucleotide sequence containing a series of TATA, about 25 nucleotides upstream from the transcriptional start point.
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